Relationships between the structural characteristic of curcumins that affect cell proliferation of hepatocarcinoma cells

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dc.contributor.author	Ramirez-Tagle, Rodrigo
dc.contributor.author	Alvarado-Soto, Leonor
dc.contributor.author	Santibanez, Juan F.
dc.contributor.author	Echeverria, Cesar
dc.date.accessioned	2024-09-12T03:39:28Z
dc.date.available	2024-09-12T03:39:28Z
dc.date.issued	2023
dc.identifier.issn	0001-9704
dc.identifier.uri	https://repositorio.uss.cl/handle/uss/11427
dc.description	Publisher Copyright: © 2023 Asociacion de Quimicos del Instituto Quimico de Sarria. All rights reserved.
dc.description.abstract	Relationships between the structural characteristic of curcumin and dimethoxycurcumin and their antitu-moral activity were studied. Treatment of HepG2 cells for 24 h with the curcumin and dimethoxycurcumin resulted in apoptosis induction and dose-dependent inhibition of cell proliferation. The calculated docking and the DFT method, suggest a structure-activity relationship between the activities of dimethoxycurcumin and curcumin structure and the apoptosis in HepG2 cells.	en
dc.language.iso	eng
dc.relation.ispartof	vol. 80 Issue: no. 599 Pages: 174-179
dc.source	Afinidad
dc.title	Relationships between the structural characteristic of curcumins that affect cell proliferation of hepatocarcinoma cells	en
dc.title.alternative	Relaciones entre las caracteristicas estructurales de las curcuminas que afectan la proliferacion celular de las celulas de hepatocarcinoma	es
dc.type	Artículo
dc.identifier.doi	10.55815/417980
dc.publisher.department	Facultad de Ingeniería, Arquitectura y Diseño

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