Mechanoautophagy : Synergies Between Autophagy and Cell Mechanotransduction at Adhesive Complexes

Abstract

Cells are exposed and respond to various mechanical forces and physical cues stemming from their environment. This interaction has been seen to differentially regulate various cellular processes for maintenance of homeostasis, of which autophagy represents one of the major players. In addition, autophagy has been suggested to regulate mechanical functions of the cells including their interaction with the environment.