Resumen: A reduced power system’s inertia represents a big issue for high penetration levels of renewable generation sources. Recently, load frequency controllers (LFCs) and their design have become crucial factors for stability and supply reliability. Thence, a new optimized multiloop fractional LFC scheme is provided in this paper. The proposed multiloop LFC scheme presents a two-degree-of-freedom (2DOF) structure using the tilt–integral–derivatives with filter (TIDN) in the first stage and the tilt–derivative with filter (TDN) in the second stage. The employment of two different loops achieves better disturbance rejection capability using the proposed 2DOF TIDN-TDN controller. The proposed 2DOF TIDN-TDN method is optimally designed using the recent powerful marine predator optimizer algorithm (MPA). The proposed design method eliminates the need for precise modeling of power systems, complex control design theories, and complex disturbance observers and filter circuits. A multisourced two-area interlinked power grid is employed as a case study in this paper by incorporating renewable generation with multifunctionality electric vehicle (EV) control and contribution within the vehicle-to-grid (V2G) concept. The proposed 2DOF TIDN-TDN LFC is compared with feature-related LFCs from the literature, such as TID, FOTID, and TID-FOPIDN controllers. Better mitigated frequency and tie-line power fluctuations, faster response, lower overshot/undershot values, and shorter settling time are the proven features of the proposed 2DOF TIDN-TDN LFC method.