Resumen: Water scarcity and related climate volatility are growing constraints on agricultural production landscapes around the world. While the adaptation options available are often dictated by system context, in many places broad-scale transformations are occurring in response to water-related pressures. We sought contributions from across regions, agricultural system types, and scientific disciplines to examine agricultural land use transitions driven by water scarcity, including the tradeoffs associated with alternative land uses; impacts on food production, environment, and society; innovations that can buffer risk; and considerations for planning and implementation. The research presented in this collection highlights the spectrum of policy and practice changes that are needed to facilitate beneficial land use transitions and system transformations, from quantifying risks, to evaluating multidimensional tradeoffs, to developing socio-technical policy bundles to maximize co-benefits.