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dc.contributor.author Villagrán, Marcelo
dc.contributor.author Petermann-Rocha, Fanny
dc.contributor.author Mardones, Lorena
dc.contributor.author Garrido-Méndez, Alex
dc.contributor.author Martorel, Miquel
dc.contributor.author Uloa, Natalia
dc.contributor.author Santos, José Luis
dc.contributor.author Pérez-Bravo, Francisco
dc.contributor.author Celis-Morales, Carlos
dc.date.accessioned 2024-09-26T00:54:10Z
dc.date.available 2024-09-26T00:54:10Z
dc.date.issued 2018-11
dc.identifier.issn 0034-9887
dc.identifier.uri https://repositorio.uss.cl/handle/uss/13996
dc.description Publisher Copyright: © 2018, Sociedad Medica de Santiago. All rights reserved.
dc.description.abstract Background: Fat-mass-associated-gene (FTO) is associated with higher energy intake and specific food preferences. Aim: To investigate the association of the FTO genotype with energy intake, macronutrient and alcohol consumption. Material and Methods: Four hundred and nine participants of the GENADIO (Genes, Environment, Diabetes and Obesity) study were included. Energy intake, macronutrient and alcohol consumption were the outcomes of interest. The association of FTO (rs9939609) genotype with these outcomes was investigated using linear regression analyses, adjusting for confounding variables. Results: After adjusting for socio-demographic factors, being a carrier of the risk allele for the FTO gene was associated with a higher energy intake (173 kcal per each extra copy of the risk variant [95% confidence intervals (CI): 45; 301], (P = 0.008). After adjusting for lifestyle factors and body mass index, the association was slightly attenuated but remained significant (144 kcal [95% CI: 14; 274], p = 0.030). Conclusions: The FTO genotype is associated with a higher energy intake. en
dc.language.iso spa
dc.relation.ispartof vol. 146 Issue: no. 11 Pages: 1252-1260
dc.source Revista Medica de Chile
dc.title Asociación entre el polimorfismo rs9939609 del gen FTO con la ingesta energética, macronutrientes y consumo de alcohol en población chilena es
dc.title.alternative Association of the FTO (rs9939609) genotype with energy intake en
dc.type Artículo
dc.identifier.doi 10.4067/S0034-98872018001101252


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